TheH-28G Evolution Turret can act as a ward, although it is not recommended since the turrets are not invisible and attack enemies on sight.
Good H-28G Evolution Turret placement is crucial to their effectiveness. For example, placing one at the back end of your minion wave would make the turrets near useless (as the enemy minions are far away from the turret).
H-28G Evolution Turret, when set up before minions appear, can be used to disrupt the enemy jungler, forcing an earlier recall, and giving info on where the jungler has been. Note that setting a new turret in your lane before H-28G Evolution Turret is at rank 3 will remove the old turret.
The amount of damage dealt by your turrets is based on when you place them. Make sure you use all your elixirs, or if you have an ally such as Sona to have them boost your ability power before placing them.
Keeping turrets clustered is good against non-AoE based champions. Keeping them away from the minion path cuts down the AoE's effectiveness even more. A tight cluster can block skillshots such as Dark Binding or Mystic Shot, but are susceptible to AoE spells such as Tormented Soil.
Hextech Micro-Rockets will hit the 3 closest enemy units, so a smart opponent will try to keep at least 3 minions in between you and him. To ensure a hit against a smart opponent, fire off your rockets right after the 3rd minion dies before they have the chance to back out.
CH-1 Concussion Grenade stun is difficult to land by itself; throwing it after allied disables have been placed guarantees success. Being closer to the target area is also helpful as it lessens the travel time.
Holding the lane is highly recommended as it is where Heimerdinger shines, being able to regenerate the turrets' health and himself.
Since Heimerdinger can heal the turrets (not just his own), he can stand guard at the turret to regen its health when damaged, and also push the wave of minions with his turrets so they can weaken the enemies turret.
Starting off with a Regrowth Pendant will allow you to remain in lane for a long while, due to its synergy with your passive, however you will run out of mana more quickly. This is recommended for more defensive laning.
Alternatively, players can opt for a Mana Manipulator early on, as opposed to the Meki Pendant for the Tear of the Goddess. While Heimerdinger will lose out on AP, the Mana Manipulator can be built into a Soul Shroud. With the 10% cooldown reduction aura it will synergize with UPGRADE!!!'s passive and provides your teammates it as well. The health bonus can also allow Heimerdinger to survive longer while the 12 mana per five aura is also handy for mana dependent teams.
CH-1 Concussion Grenade can be used to reveal a large area. This combined with its long range make it excel at scouting brush or jungle areas.
Leaving a lane to buy items can be more beneficial to your lane if you have the summoner spell Teleport. By placing your turrets in a bush out of sight and recalling within the sight of your enemies then buying items and using Teleport back to the hidden turret can cause your lane enemies to over extend trying to kill your partner when you come out of the bush and kill them.
Before leaving a lane, place both turrets and then Teleport back to one of your turrets being attacked since it will be invulnerable during the teleport time.