When the champion against you has a blink (eg. Ezreal), and he attempts to engage you, throw a SmokescreenSmokescreen to where he blinked, and quickly dash away leaving your opponent visionless.
By using smart cast, you can cast Buckshot and Quickdraw together in such a way that you dash back while shooting the three bullets of Buckshot in front of you. Use this combo to finish off enemies with low hp and make a quick escape.
Also, save your spells until outside of SmokescreenSmokescreen as the vision loss can lead to the loss of your target.
If you are a champion that plans to cast a supportive ability on an ally, considering staying close to the ally so that SmokescreenSmokescreen cannot stop you from seeing them and thus casting onto them.
Avoid extended skirmishes with Graves as he gains armor and magic resistance as the battle rages on from True GritTrue Grit. The bonus armor and magic resist can change an expected kill to a close call.